Tagging of Histopathology Specimens with Light-Activated RFID p-Chips

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44GM096580-02
Agency Tracking Number: R44GM096580
Amount: $1,172,636.00
Phase: Phase II
Program: SBIR
Awards Year: 2012
Solicitation Year: 2012
Solicitation Topic Code: NIGMS
Solicitation Number: PA11-096
Small Business Information
DUNS: 27661870
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (732) 355-0100
Business Contact
Phone: (732) 355-0100
Email: mandecki@pharmaseq.com
Research Institution
DESCRIPTION (provided by applicant): The purpose of the present project is to develop and validate the use of ultra-small RFID chips to tag and track tissue cassettes and glass slides that are used in histopathology laboratories. The system is based on thePharmaSeq laser light-activated microtransponder, also known as p-Chip . The chip's major advantages are its small size (500 m x 500 m x 100 m), unitary design, inertness, ease of use and very low cost. The system consists of the p-Chip-tagged glassslides and tissue cassettes, a stationary reader, a portable reader for trays with slides, and associated software that allows integration with common database software. The main goals of the project are to: 1) develop semi-automated methods of attachingp-Chips to slides and cassettes, 2) build advanced prototypes of the ID reader (wand) and improve key features, such as the form factors for reading each type of container, 3) improve the design of the p-Chip to increase the read range and refine methods of their post-fabrication processing, and 4) conduct extensive pilot test studies with outside collaborators to validate the system. The ID readers will have a modified optical system and will feature wireless communication between the reader and a workstation or central computer. The adoption of the system will improve reliability for tagging and tracking tissue samples. PUBLIC HEALTH RELEVANCE: Pathology specimens play an important role in research and medical practice, and are analyzed and storedin increasingly large quantities. The new PharmaSeq RFID tracking system has the potential to greatly improving the reliability of maintaining the providence for large numbers of samples using a new type of electronic identification system. Medical studies, including cancer research, clinical investigations, in vitr diagnostics and drug discovery fields will all benefit.

* Information listed above is at the time of submission. *

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