Genetic sex reversal of rainbow trout

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$84,329.00
Award Year:
2012
Program:
SBIR
Phase:
Phase I
Contract:
2012-00223
Agency Tracking Number:
2012-00223
Solicitation Year:
2012
Solicitation Topic Code:
8.7
Solicitation Number:
USDA-NIFA-SBIR-003497
Small Business Information
TROUTLODGE INC
12000 MCCUTCHEON RD, Bonney Lake, WA, 98391-8114
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
075733204
Principal Investigator:
Kyle Martin
Research Geneticist
(253) 826-0145
kyle@troutlodge.com
Business Contact:
Kyle Martin
Research Geneticist
(253) 826-0145
kyle@troutlodge.com
Research Institution:
Stub




Abstract
A majority of rainbow trout produced in the US are derived from all-female stocks due to improved harvest traits and efficiency over mixed sex stocks. The development of all-female stocks currently relies on the use of the testosterone derivative 17 & #945; & #8722;methyltestosterone, however the long term use of this method is not guaranteed as regulations governing the use of the substance are becoming more stringent. Troutlodge Inc. in cooperation with researchers at Washington State University, has isolated rare XX individuals that develop as functional males. The sex ratio of progeny produced by these rare individuals indicates an autosomal recessive mutation causing the maleness. We will test the feasibility and functionality of using these individuals as a new method of production of all female lines without the use of hormones. Fine mapping in an attempt to identify the specific sex-reversal locus would occur in Phase II of the grant.

* information listed above is at the time of submission.

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