Micro-encapsulation and Nanotechnology Treatments to Prevent Proteolytic Diseases of Aquatic Animals

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$269,392.00
Award Year:
2012
Program:
SBIR
Phase:
Phase II
Contract:
2012-02170
Award Id:
n/a
Agency Tracking Number:
2012-02170
Solicitation Year:
2012
Solicitation Topic Code:
8.7
Solicitation Number:
USDA-NIFA-SBIR-003621
Small Business Information
17806 NE 26TH ST, Redmond, WA, 98052-5848
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
179038190
Principal Investigator:
David Powell
Vice President of Research
(425) 883-9896
davidp@profishent.com
Business Contact:
Roger Palm
President
(425) 883-9896
rogerp@profishent.com
Research Institution:
Stub




Abstract
Many fungal and bacterial pathogens produce proteolytic enzymes that facilitate penetration into fish skin or eggshells. These diseases are a major and growing challenge to sustainable aquaculture in the United States. Our Phase I research results demonstrated the feasibility of new, non-toxic, disease prevention and treatment strategies. The key is our focus on safe, natural materials combined with innovative delivery systems. We propose to enhance the efficacy of the treatments identified in Phase I by applying recent advances in particle chemistry and nanotechnology. First, we will examine the efficacy of our latest formulation discoveries against an array of pathogenic Saprolegnia fungi from diverse geographic areas to validate their widespread applicability. Second, we will examine unique enzyme systems and test for anti-fungal activity. Third, we will work to magnify the therapeutic potency of our formulations by combining them to non-toxic micro- or nanoparticles. Fourth, these treatment systems will be tested in catfish and trout for safety and efficacy. Lastly, this agriculturally-related manufacturing technology will be commercialized by developing initial prototype products and field testing them in conjunction with ProFishent's Phase III collaborator, AquaTactics, LLC. These treatments should promote an expansion of the number of cultured species, make the harvest volume more predictable, and increase the productivity of private and public sector aquaculture in the U.S.A.

* information listed above is at the time of submission.

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