Micro-encapsulation and Nanotechnology Treatments to Prevent Proteolytic Diseases of Aquatic Animals

Award Information
Agency: Department of Agriculture
Branch: N/A
Contract: 2012-02170
Agency Tracking Number: 2012-02170
Amount: $269,392.00
Phase: Phase II
Program: SBIR
Awards Year: 2012
Solitcitation Year: 2012
Solitcitation Topic Code: 8.7
Solitcitation Number: USDA-NIFA-SBIR-003621
Small Business Information
17806 NE 26TH ST, Redmond, WA, 98052-5848
Duns: 179038190
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 David Powell
 Vice President of Research
 (425) 883-9896
Business Contact
 Roger Palm
Title: President
Phone: (425) 883-9896
Email: rogerp@profishent.com
Research Institution
Many fungal and bacterial pathogens produce proteolytic enzymes that facilitate penetration into fish skin or eggshells. These diseases are a major and growing challenge to sustainable aquaculture in the United States. Our Phase I research results demonstrated the feasibility of new, non-toxic, disease prevention and treatment strategies. The key is our focus on safe, natural materials combined with innovative delivery systems. We propose to enhance the efficacy of the treatments identified in Phase I by applying recent advances in particle chemistry and nanotechnology. First, we will examine the efficacy of our latest formulation discoveries against an array of pathogenic Saprolegnia fungi from diverse geographic areas to validate their widespread applicability. Second, we will examine unique enzyme systems and test for anti-fungal activity. Third, we will work to magnify the therapeutic potency of our formulations by combining them to non-toxic micro- or nanoparticles. Fourth, these treatment systems will be tested in catfish and trout for safety and efficacy. Lastly, this agriculturally-related manufacturing technology will be commercialized by developing initial prototype products and field testing them in conjunction with ProFishent's Phase III collaborator, AquaTactics, LLC. These treatments should promote an expansion of the number of cultured species, make the harvest volume more predictable, and increase the productivity of private and public sector aquaculture in the U.S.A.

* information listed above is at the time of submission.

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