SBIR Phase II: Reel-to-Reel Assembly of Lab-on-a-Film Diagnostic Tests

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 1230152
Agency Tracking Number: 1230152
Amount: $498,780.00
Phase: Phase II
Program: SBIR
Awards Year: 2012
Solicitation Year: 2012
Solicitation Topic Code: BC
Solicitation Number: N/A
Small Business Information
Akonni
7991 Heather Mist Dr, Severn, MD, 21144-0000
DUNS: 154704444
HUBZone Owned: Y
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Christopher Cooney
 (301) 273-8847
 ccooney@akonni.com
Business Contact
 Christopher Cooney
Phone: (301) 273-8847
Email: ccooney@akonni.com
Research Institution
 Stub
Abstract
This Small Business Innovation Research (SBIR) Phase II project is designed to investigate the feasibility of manufacturing a Lab-on-a-Film? microarray device on a reel-to-reel assembly line. Reel-to-reel manufacturing has the potential to drastically reduce device cost because hundreds of parts per hour can be assembled. The goal of this project is to demonstrate the feasibility of manufacturing valve-less molecular lateral flow cells for gel drop microarrays using reel-to-reel assembly equipment. At the conclusion of this project, the goal is to demonstrate feasibility by positively identifying clinical samples for infectious disease on reel-to-reel manufactured Lab-on-a-Film? assemblies. The broader impact/commercial potential of this project is the potential to distribute quality diagnostics to an expanded population. With cost being such an important factor in today?s healthcare system, the need to investigate new avenues for offering quality diagnostics arises with increasing urgency. This challenge may become a catalyst for a new multiplexing paradigm in molecular diagnostics. A range of possibilities apply to this paradigm such as infectious disease testing for multiple organisms, pathogenic genotyping, genetic testing, forensics, environmental screening, agriculture testing, and biodefense applications. Addressing not only the usability of the end test, but also the manufacturing process is a means to be competitive in a 50 billion dollar global diagnostics market space.

* information listed above is at the time of submission.

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