Improved Dried Biological Specimen Materials, Recovery and Processing for Diagnostics

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$149,665.00
Award Year:
2012
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-12-C-0025
Award Id:
n/a
Agency Tracking Number:
11SB2-0114
Solicitation Year:
2011
Solicitation Topic Code:
SB112-005
Solicitation Number:
2011.2
Small Business Information
696 Amity Road, Route 63, Bethany, CT, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
783630189
Principal Investigator:
JosephBango
President
(203) 393-9666
jbango@ctanalytical.com
Business Contact:
JosephBango
President
(203) 393-9666
jbango@ctanalytical.com
Research Institute:
Stub




Abstract
Dried blood spot (DBS) analysis has gained recognition in recent years in basic science and clinical diagnostics. This impetus relies upon its numerous advantages over the collection, transport and storage of blood samples obtained by conventional venipuncture. Although there is wide-spread interest in DBS, optimization of sample collection and extraction methods, as well as, the subsequent analyses by standard analytical methods is still in its infancy. Therefore, preliminary experiments comparing different extraction methods (e.g. alcohol incubation and electrospray transfer) were carried out and analyzed by enzyme linked immunosorbent assay (ELISA). We propose that electrospray ionization-transfer offers superior extraction to that of the standard chemical methods by 1) efficient extraction of analytes from the DBS substrate and 2) concentration of the analyte.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government