Label-free Immunoassay-Based Assessment for Chromate Exposure

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$149,992.00
Award Year:
2012
Program:
SBIR
Phase:
Phase I
Contract:
FA8222-12-C-0019
Award Id:
n/a
Agency Tracking Number:
F121-220-0322
Solicitation Year:
2012
Solicitation Topic Code:
AF121-220
Solicitation Number:
2012.1
Small Business Information
7610 Eastmark Drive, College Station, TX, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
184758308
Principal Investigator:
Jinseong Kim
Sr. Scientist
(979) 764-2200
jinseong.kim@lynntech.com
Business Contact:
G. Hisaw
Sr. Contracts Adminitrator
(979) 764-2218
renee.hisaw@lynntech.com
Research Institution:
Stub




Abstract
ABSTRACT: Several million workers worldwide are estimated to be exposed to chromium compounds. At present there is a medical test that can determine the total amount of chrome in the human body. There are no known physiological tests to determine the exposure of the human body to hexavalent chrome which is a human carcinogen and exposures are regulated by OSHA standard. Lynntech proposes (i) to determine physiological markers for exposure to hexavalent chrome, and (ii) to develop a physiological testing system to determine the exposure of human body to hexavalent chrome using innovative immunoassay platform technology. This system does not require interference-prone colorimetric device or labeling agents like chemiluminescence, fluorescence, nanoparticles, dyes, etc. In addition, the assay platform is simple and not labor intensive, thus, it can be modified to detect multiple antigens simultaneously. It is envisioned that entire system be automatically controlled. During the Phase I project Lynntech will establish the feasibility of the testing system determining the workplace exposure to chromate using biomarkers identified. BENEFIT: Lynntech"s physiological testing system quantifiably determining chromate exposure has significant dual use commercialization potential to the federal government and private industries. Military applications include determination of exposure of personnel to chromate and mitigation of exposure effects to personnel screening. Civilian applications include screening/confirmation of public & agricultural workers exposure to chromate.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government