Topical Soft Tissue Treatment Technology

Award Information
Agency:
Department of Defense
Amount:
$99,999.00
Program:
SBIR
Contract:
W81XWH-12-C-0031
Solitcitation Year:
2011
Solicitation Number:
2011.2
Branch:
Army
Award Year:
2012
Phase:
Phase I
Agency Tracking Number:
A112-103-0114
Solicitation Topic Code:
A11-103
Small Business Information
Physical Optics Corporation
1845 W. 205th Street, Torrance, CA, -
Hubzone Owned:
N
Woman Owned:
Y
Socially and Economically Disadvantaged:
N
Duns:
153865951
Principal Investigator
 Anya Asanbaeva
 Director
 (310) 320-3088
 psproposals@poc.com
Business Contact
 Gordon Drew
Title: Chief Financial Officer
Phone: (310) 320-3088
Email: gedrew@poc.com
Research Institution
N/A
Abstract
Development of readily forward-deployable therapeutic measures to enhance wound healing could promote earlier restoration to health and return to duty. To address the Army need for a topical wound treatment with recombinant heat shock proteins (rHSPs) that can be applied to wounds to promote wound healing, Physical Optics Corporation (POC) proposes to develop a new topical soft tissue treatment (TOSTT) technology. The applied TOSTT releases rHSPs into the extracellular compartment of the wound where they come into direct contact with cellular components essential to the repair process. Repeat applications of TOSTT to the wound area sustain the elevated extracellular pools of HSPs and thereby exert a sustained effect. The innovation in the method of wound healing using rHSP application to the wound and the new topical formulation to effectively deliver the active ingredient will enable the TOSTT to directly and effectively enhance the wound healing process. As a result, this topical treatment is of high therapeutic efficacy and can be readily transitioned to clinical markets. In Phase I, POC will develop the formulation and demonstrate its efficacy in a pilot animal study. In Phase II, further therapeutic efficacy characterization of TOSTT will be performed with detailed animal studies.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government