Archive of Samples for Long-term Preservation of RNA and Other Nucleic Acids

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-12-C-0030
Agency Tracking Number: A112-107-0888
Amount: $99,660.00
Phase: Phase I
Program: SBIR
Awards Year: 2012
Solicitation Year: 2011
Solicitation Topic Code: A11-107
Solicitation Number: 2011.2
Small Business Information
Biomatrica, Inc.
5627 Oberlin Drive, Suite 120, San Diego, CA, -
DUNS: 793908489
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Rolf Muller
 CSO
 (858) 550-0308
 rmuller@biomatrica.com
Business Contact
 Judy Muller-Cohn
Title: CFO
Phone: (858) 550-0308
Email: jmullercohn@biomatrica.com
Research Institution
 Stub
Abstract
The objective is to develop approaches are sought for sample preservation of nucleic acids from blood products or other sample for storage at room temperature conditions. The goals of the project are to: 1) determine preferable tissue for nucleic acid archiving; 2) investigate sample collection protocol, processing, of the selected tissue; and 3) initially define key potential aspects of storage conditions for preservation of nucleic acids. In addition, we will develop a completely integrated ambient temperature workflow from collection, transport to storage to avoid any cold-chain handling. This complete ambient workflow can be achieved through the integration of advanced thermo-stability products currently in Biomatrica's product development pipeline. The overall objective is the development of workflow which protects nucleic acids, in particular RNA from degradation during collection to sample archiving and determine its feasibility for large scale implementation.

* information listed above is at the time of submission.

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