NANOPARTICLE-AMPLIFIED MULTIPLEXED SENSOR FOR EARLY CANCER DETECTION

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$149,897.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
N43CO201000127
Award Id:
96445
Agency Tracking Number:
N43CO201000127
Solicitation Year:
n/a
Solicitation Topic Code:
NCI
Solicitation Number:
n/a
Small Business Information
111 DOWNEY ST, NORWOOD, MA, 02062-
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
076603836
Principal Investigator:
MICHAEL WILSON
(781) 769-9450
drauh@eiclabs.com
Business Contact:
Research Institution:
n/a
Abstract

The measurement of panels of biomarkers has promise for increased diagnostic value in cancer detection and treatment compared to the measurement of single markers. Furthermore, to increase their effectiveness in the early detection of cancer, where the markers may have very low concentrations, or where small changes in concentration may be significant, assays with higher sensitivity are needed.    The objective of this proposal is to develop a nanotechnology-based biosensor to simultaneously measure the concentrations of multiple tumor markers (TMs) with high sensitivity. The system consists of an electrochemical array for mulitanalyte measurement, nanoparticle assay labels to provide significant assay signal amplification, and a portable device for reading and quantifying the assays.

* information listed above is at the time of submission.

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