IGF::OT::IGF OTHER FUNCTIONS SCALABLE AUTOMATED BRAIN TUMOR SEGMENTATION

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$199,969.00
Award Year:
2012
Program:
SBIR
Phase:
Phase I
Contract:
N43CO120032
Agency Tracking Number:
N43CO120032
Solicitation Year:
2012
Solicitation Topic Code:
NCI
Solicitation Number:
n/a
Small Business Information
INFOTECH SOFT, INC.
INFOTECH SOFT, INC., 1201 Brickell Ave, MIAMI, FL, 33131-
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
035354070
Principal Investigator:
PATRICIA BUENDIA
(305) 371-5111
PATRICIA.BUENDIA@INFOTECHSOFT.COM
Business Contact:
PATRICIA BUENDIA
(305) 371-5111
PATRICIA.BUENDIA@INFOTECHSOFT.COM
Research Institution:
Stub




Abstract
Brain tumor segmentation in Magnetic Resonance Imaging is an important task for neurosurgeons, oncologists, and radiologists to assess disease burden and measure tumor response to treatment. In 2008, over 237,000 individuals worldwide are estimated to havebeen diagnosed with malignant brain and central nervous system tumors with over 174,000 deaths. Detection of brain tumors with the exact location and orientation is extremely important for effective diagnosis, treatment planning, and analysis of treatmenteffectiveness; however, manual delineation of the tumor takes considerable time and is prone to error and wide variability. The overall goal of this proposal is to develop a scalable and automated approach for the segmentation of brain tumors based on Hidden Markov Models (HMMs). The objectives of the project are: 1) Develop a tumor segmentation approach based on a novel utilization of HMMs for automated segmentation of multi-sequence brain MRI data for accurate and robust determination of tumor volume; 2)Design a MapReduce model for the HMM-based brain tumor segmentation approach to enable scalable development of the segmentation processes in a cluster environment; 3) Evaluate the HMM-based brain tumor segmentation framework in terms of accuracy, robustness, and performance in the context of multi-sequence MRI data.

* information listed above is at the time of submission.

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