Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N43CO120032
Agency Tracking Number: N43CO120032
Amount: $199,969.00
Phase: Phase I
Program: SBIR
Awards Year: 2012
Solicitation Year: 2012
Solicitation Topic Code: NCI
Solicitation Number: N/A
Small Business Information
INFOTECH SOFT, INC., 1201 Brickell Ave, MIAMI, FL, 33131-
DUNS: 035354070
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (305) 371-5111
Business Contact
Phone: (305) 371-5111
Research Institution
Brain tumor segmentation in Magnetic Resonance Imaging is an important task for neurosurgeons, oncologists, and radiologists to assess disease burden and measure tumor response to treatment. In 2008, over 237,000 individuals worldwide are estimated to havebeen diagnosed with malignant brain and central nervous system tumors with over 174,000 deaths. Detection of brain tumors with the exact location and orientation is extremely important for effective diagnosis, treatment planning, and analysis of treatmenteffectiveness; however, manual delineation of the tumor takes considerable time and is prone to error and wide variability. The overall goal of this proposal is to develop a scalable and automated approach for the segmentation of brain tumors based on Hidden Markov Models (HMMs). The objectives of the project are: 1) Develop a tumor segmentation approach based on a novel utilization of HMMs for automated segmentation of multi-sequence brain MRI data for accurate and robust determination of tumor volume; 2)Design a MapReduce model for the HMM-based brain tumor segmentation approach to enable scalable development of the segmentation processes in a cluster environment; 3) Evaluate the HMM-based brain tumor segmentation framework in terms of accuracy, robustness, and performance in the context of multi-sequence MRI data.

* Information listed above is at the time of submission. *

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