IGF::OT::IGF OTHER FUNCTIONS ENUMERAL PHASE I, TOPIC 309, DETECTION OF MULTIPLE ANALYTES FROM SMALL TISSUE SAMPLES

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$199,833.00
Award Year:
2012
Program:
SBIR
Phase:
Phase I
Contract:
N43CO120073
Agency Tracking Number:
N43CO120073
Solicitation Year:
2012
Solicitation Topic Code:
NCI
Solicitation Number:
n/a
Small Business Information
ENUMERAL BIOMEDICAL CORPORATION
ENUMERAL BIOMEDICAL CORPORATION, 1450 BROADWAY, FL 24, NEW YORK, NY, 10018-2224
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
965560837
Principal Investigator:
ARTHUR TINKELENBERG
(347) 277-4787
ARTHUR@ENUMERAL.COM
Business Contact:
ARTHUR TINKELENBERG
(347) 277-4787
ARTHUR@ENUMERAL.COM
Research Institution:
Stub




Abstract
Cancer is a leading cause of death that affects millions of lives across the world. It is a complex disease that is likely to require multifactorial measurements for earlier and more accurate diagnosis and patient stratification. Tissue biopsies and fine needle aspirates are commonly collected clinically, but existing multi-analyte technology platforms are ill-equipped to derive meaningful information from single samples. The goal of this proposal is to characterize Enumeral s technology for the measurement of multiple analytes on clinical samples and to generate a design for an automated prototype system to be used in Phase II. Enumeral s platform is ideally suited for the measurement of small samples, as it can accept and analyze cell samples of any size from any tissue in the body. The system will be characterized with commercially available reagents and tested on biopsy samples to measure secreted proteins, surface markers, and gene expression. With the mortality associated with cancer and the sheervolume of clinical samples taken on an annual basis, the advancement of technologies for the analysis of small tissue samples has the potential to advance the understanding of cancer progression and open new doors for diagnostic and treatment paradigms.

* information listed above is at the time of submission.

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