Encapsulation Technology for Increased Environmental Stability of Vertebrate Cells

Award Information
Agency:
Department of Defense
Amount:
$99,999.00
Program:
SBIR
Contract:
W9132T-13-C-0004
Solitcitation Year:
2012
Solicitation Number:
2012.2
Branch:
Army
Award Year:
2013
Phase:
Phase I
Agency Tracking Number:
A122-090-0468
Solicitation Topic Code:
A12-090
Small Business Information
Luna Innovations Incorporated
1 Riverside Circle, Suite 400, Roanoke, VA, -
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
627132913
Principal Investigator
 Blaine Butler
 Principal Investigator
 (434) 220-2509
 butlerb@lunainnovations.com
Business Contact
 Shirley Evans
Title: Sr. Contract Administrator
Phone: (540) 961-6724
Email: submissions302@lunainnovations.com
Research Institution
 Stub
Abstract
Luna Innovations is developing stabilization technology for increased long-term storage of various biological moieties (e.g. enzymes, nucleic acids, and whole cells). This unique stabilization matrix allows for extended cell viability lifetime, minimizing cell maintenancerequirements while retaining physiological activity. The proposed encapsulated cell technology will provide significant improvements in cell lifetime, operational stability, with decreased maintenance requirements, and is easily integrated into a variety of sensing based platforms allowing for optical and/or electrical reporting metrics. During Phase I Luna will demonstrate stable long-term cell viability with enhanced environmental stability for a variety of cell lines (including mammalian cells) for a minimum of 8 weeks while still retaining physiological cellular activity. Phase II will focus on extending the cell viability and function to a minimum of 6 months for an increased variety of cell types while also working to integrate the stabilization technology into a microfluidic chip for incorporation into the SafePort water analysis system.

* information listed above is at the time of submission.

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