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Development of a field-appropriate biosensor for detecting Mycobacterium tuberculosis infection

Award Information
Agency: Department of Defense
Branch: Defense Health Agency
Contract: FA8650-13-C-6392
Agency Tracking Number: O2-1337
Amount: $750,000.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: OSD11-H05
Solicitation Number: 2011.2
Solicitation Year: 2011
Award Year: 2013
Award Start Date (Proposal Award Date): 2013-04-15
Award End Date (Contract End Date): 2015-07-10
Small Business Information
3815 Technology Blvd Suite 1050
Lansing, MI -
United States
DUNS: 968162672
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Houng-Yau Mei
 (734) 649-2486
Business Contact
 Fred Beyerlein
Title: CEO
Phone: (734) 223-2591
Research Institution

nanoRETE is a developing a nanoparticle-based biosensor technology platform that has the ability for real-time detection of pathogens. Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) that primarily affects the lungs. In Phase I research, nanoRETE demonstrated proof-of-concept of an electrochemical nano-bead biosensor for measuring plasma cytokine and chemokine concentrations that have been identified as biomarkers of Mtb infection. In Phase II research, an optimized electrochemical multiplex assay for rapid TB detection will be developed using a prototype biosensor cartridge. The prototype will then be tested with clinical samples. Finally, a fully-integrated"sample in-results out"TB screening device will be designed and experimental plans for Phase III laid out.

* Information listed above is at the time of submission. *

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