Development of a field-appropriate biosensor for detecting Mycobacterium tuberculosis infection

Award Information
Agency:
Department of Defense
Branch
Defense Health Program
Amount:
$750,000.00
Award Year:
2013
Program:
SBIR
Phase:
Phase II
Contract:
FA8650-13-C-6392
Award Id:
n/a
Agency Tracking Number:
O2-1337
Solicitation Year:
2011
Solicitation Topic Code:
OSD11-H05
Solicitation Number:
2011.2
Small Business Information
3815 Technology Blvd, Suite 1050, Lansing, MI, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
968162672
Principal Investigator:
Houng-Yau Mei
COO
(734) 649-2486
hmei@nanorete.com
Business Contact:
Fred Beyerlein
CEO
(734) 223-2591
fbeyerlein@nanorete.com
Research Institution:
Stub




Abstract
nanoRETE is a developing a nanoparticle-based biosensor technology platform that has the ability for real-time detection of pathogens. Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) that primarily affects the lungs. In Phase I research, nanoRETE demonstrated proof-of-concept of an electrochemical nano-bead biosensor for measuring plasma cytokine and chemokine concentrations that have been identified as biomarkers of Mtb infection. In Phase II research, an optimized electrochemical multiplex assay for rapid TB detection will be developed using a prototype biosensor cartridge. The prototype will then be tested with clinical samples. Finally, a fully-integrated"sample in-results out"TB screening device will be designed and experimental plans for Phase III laid out.

* information listed above is at the time of submission.

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