Low Gravity Drug Stability Analyzer

Award Information
Agency: National Aeronautics and Space Administration
Branch: N/A
Contract: NNX13CA52P
Agency Tracking Number: 125155
Amount: $125,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2013
Solicitation Year: 2012
Solicitation Topic Code: H12.05
Solicitation Number: N/A
Small Business Information
CT, Middletown, CT, 06457-1548
DUNS: 178766200
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Stuart Farquharson
 Principal Investigator
 (860) 635-9800
Business Contact
 Stuart Farquharson
Title: President
Phone: (860) 635-9800
Email: stu@rta.biz
Research Institution
The overall goal of this proposed program (through Phase III) is to build a space-worthy Drug Stability Analyzer that can determine the extent of drug degradation. It will be able to monitor the drug active pharmaceutical ingredient (API) and its degradation product concentrations as a function of time, as well as determine if a drug is suitable for use (likely based on the presence of 90% or more of the original API concentration). This will be accomplished by designing and building a rugged, small, light weight, low power, easy to use analyzer with appropriate software, which can identify and quantify API and degradation products with little or no sample handling in 1 minute. Feasibility will be demonstrated during Phase I by successfully measuring acetaminophen, azithromycin, epinephrine, lidocaine, and their degradation products at percent level concentrations.The overall goal of the Phase II program is to build a working prototype Drug Stability Analyzer that is suitable for space deployment (e.g. aboard the ISS) and capable of monitoring drug degradation. The ability of the analyzer to nondestructively quantify the amount of the API and the degradation products, would also allow assessing drug potency at the time of use to ensure crewmember safety. The Drug Stability Analyzer will be transitioned from a Technology Readiness Level 3 to a 7 (ground tested) from the beginning to the end of the program.

* Information listed above is at the time of submission. *

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