A High Brightness Light Source for UV-VIS Spectroscopic Imaging

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43RR028147-01
Agency Tracking Number: RR028147
Amount: $198,051.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solicitation Year: 2010
Solicitation Topic Code: NCRR
Solicitation Number: PHS2010-2
Small Business Information
ENERGETIQ TECHNOLOGY, INC.
ENERGETIQ TECHNOLOGY, INC., 7 CONSTITUTION WAY, WOBURN, MA, 01801
DUNS: 153302398
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 STEPHEN HORNE
 (781) 939-0763
 SHORNE@ENERGETIQ.COM
Business Contact
 WILLIAM HOLBER
Phone: (781) 939-0763
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Energetiq has developed an ultra-high-brightness light source for semiconductor metrology applications. This same basic technology could have broad application in biological imaging, where today's instruments are limited in optical brightness, particularly in the UV spectral region. The goal of this proposed program, A High Brightness Light Source for UV-VIS Spectroscopic Imaging is to develop a new family of light sources optimized for quantitative UV-VIS spectroscopic imaging. Our Phase I program will (i) prototype a laser-driven plasma source optimized for microscopy; (ii) design a wavelength-filtered condenser system matched to a broad-band biological microscope; then (iii) begin to demonstrate the advantages of this source in imaging of biological cells. PUBLIC HEALTH RELEVANCE: Broad-band optical microscopy is a key tool for a wide range of biological studies. However today's instruments are limited, both generally in optical brightness and in particular in the deep UV region, where high-resolution imaging spectrophotometry shows the most potential value. The goal of this proposed program, A High Brightness Light Source for UV-VIS Spectroscopic Imaging is to develop a new family of light sources optimized for quantitative UV-VIS spectroscopic imaging. Improved throughput and information content for biological assay is central to the productivity both of medical research and drug development.

* information listed above is at the time of submission.

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