A High Brightness Light Source for UV-VIS Spectroscopic Imaging

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$198,051.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
1R43RR028147-01
Award Id:
96495
Agency Tracking Number:
RR028147
Solicitation Year:
n/a
Solicitation Topic Code:
NCRR
Solicitation Number:
n/a
Small Business Information
ENERGETIQ TECHNOLOGY, INC., 7 CONSTITUTION WAY, WOBURN, MA, 01801
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
153302398
Principal Investigator:
STEPHEN HORNE
(781) 939-0763
SHORNE@ENERGETIQ.COM
Business Contact:
WILLIAM HOLBER
() -
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): Energetiq has developed an ultra-high-brightness light source for semiconductor metrology applications. This same basic technology could have broad application in biological imaging, where today's instruments are limite d in optical brightness, particularly in the UV spectral region. The goal of this proposed program, A High Brightness Light Source for UV-VIS Spectroscopic Imaging is to develop a new family of light sources optimized for quantitative UV-VIS spectroscopi c imaging. Our Phase I program will (i) prototype a laser-driven plasma source optimized for microscopy; (ii) design a wavelength-filtered condenser system matched to a broad-band biological microscope; then (iii) begin to demonstrate the advantages of thi s source in imaging of biological cells. PUBLIC HEALTH RELEVANCE: Broad-band optical microscopy is a key tool for a wide range of biological studies. However today's instruments are limited, both generally in optical brightness and in particular in the deep UV region, where high-resolution imaging spectrophotometry shows the most potential value. The goal of this proposed program, A High Brightness Light Source for UV-VIS Spectroscopic Imaging is to develop a new family of light sources optimized f or quantitative UV-VIS spectroscopic imaging. Improved throughput and information content for biological assay is central to the productivity both of medical research and drug development.

* information listed above is at the time of submission.

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