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Development of Manufacturing Technology for the Practical Application of Specialized and Environmentally Sensitive Nutrients, Enzymes, Immune-Stimulating Compounds and Biologics to Aquafeeds

Award Information
Agency: Department of Commerce
Branch: National Oceanic and Atmospheric Administration
Contract: WC-133R-13-CN-0110
Agency Tracking Number: 12-2-081
Amount: $397,510.08
Phase: Phase II
Program: SBIR
Solicitation Topic Code: 8.2.3F
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2013
Award Start Date (Proposal Award Date): 2013-09-17
Award End Date (Contract End Date): 2015-09-16
Small Business Information
PO Box 95
Gardners, PA 17324-0095
United States
DUNS: 014137475
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Matt Zeigler
 Vice President of Operations
 (717) 677-6181
Business Contact
 Matt Zeigler
Research Institution

In an effort to support the development of a domestic marine aquaculture industry, Zeigler Bros. Inc., (ZBI) proposes to continue its Phase I research by demonstrating the ability to scale up inclusion particle (IP) manufacturing. During Phase II ZBI will also demonstrate the efficacy of IOs for orally delivering phytase and probiotics to marine finfish. These efforts will directly address the primary limiting factors of the development of a domestic marine aquaculture industry; nutrient utilization, pollution, and disease management.

During Phase I ZBI did demonstrate the efficacy of a feed-based anti-viral delivery platform, significantly improving survivability of pacific white legged shrimp (Panaeus vannamel) when challenged with White Spot Syndrome Virus with lab-scale production. The next logical step is to transition into a manufacturing project, adapting the laboratory techniques and equipment into a R&D prototype inclusion particle production line (IPPL) capable of manufacturing larger batches of IPs and flexible enough to allow for multiple test molecules, such as phytase, probiotics or anti-virals.

ZBI proposes to develop the prototype manufacturing line, train employees to operate the line, manufacture multiple IP formulations containing anti-virals, phytase and probiotics separately, and manufacture complete feeds to be used in validation studies with marine aquaculture animals.

* Information listed above is at the time of submission. *

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