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Porous Membrane Electrode for Quantitative Detection of Toxins

Award Information
Agency: Department of Commerce
Branch: National Oceanic and Atmospheric Administration
Contract: WC-133R-13-CN-0111
Agency Tracking Number: 12-2-116
Amount: $400,000.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: 8.1.6N
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2013
Award Start Date (Proposal Award Date): 2013-09-13
Award End Date (Contract End Date): 2015-09-12
Small Business Information
4802 Glendarion Drive, Durham, NC, 27713-8025
DUNS: 033608972
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Thomas Stewart
 President
 (866) 861-5836
 tom@mercuryscience.com
Business Contact
 Thomas Stewart
Research Institution
N/A
Abstract
In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a potentiostat. These biosensors will be incorporated into a portable test kit for the quantitation of domoic acid. Based on performance evaluations, the assay protocol will be adjusted to provide the optimal response at appropriate detection levels. Reagent formulations will be optimized to increase signal, reduce background noise, improve reproducibility, and lengthen test kit shelf life. Following optimization, a complete prototype test kit will be assembled. Field trials using the prototype kit will be performed by potential users. Standard operating procedures for the manufacture and quality control of reagents will be established. The successful completion of Phase II will lead to the market launch of a commercially useful onsite domoic acid test kit in Phase II.

* Information listed above is at the time of submission. *

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