Porous Membrane Electrode for Quantitative Detection of Toxins

Award Information
Agency:
Department of Commerce
Amount:
$400,000.00
Program:
SBIR
Contract:
WC-133R-13-CN-0111
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
National Oceanic and Atmospheric Administration
Award Year:
2013
Phase:
Phase II
Agency Tracking Number:
12-2-116
Solicitation Topic Code:
8.1.6N
Small Business Information
Mercury Science Inc.
4802 Glendarion Drive, Durham, NC, 27713-8025
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
033608972
Principal Investigator
 Thomas Stewart
 President
 (866) 861-5836
 tom@mercuryscience.com
Business Contact
 Thomas Stewart
Research Institution
N/A
Abstract
In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a potentiostat. These biosensors will be incorporated into a portable test kit for the quantitation of domoic acid. Based on performance evaluations, the assay protocol will be adjusted to provide the optimal response at appropriate detection levels. Reagent formulations will be optimized to increase signal, reduce background noise, improve reproducibility, and lengthen test kit shelf life. Following optimization, a complete prototype test kit will be assembled. Field trials using the prototype kit will be performed by potential users. Standard operating procedures for the manufacture and quality control of reagents will be established. The successful completion of Phase II will lead to the market launch of a commercially useful onsite domoic acid test kit in Phase II.

* information listed above is at the time of submission.

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