Topical Soft Tissue Treatment Technology

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$999,856.00
Award Year:
2013
Program:
SBIR
Phase:
Phase II
Contract:
W81XWH-12-C-0031
Award Id:
n/a
Agency Tracking Number:
A2-5438
Solicitation Year:
2011
Solicitation Topic Code:
A11-103
Solicitation Number:
2011.2
Small Business Information
Photonic Systems Division, 1845 West 205th Street, Torrance, CA, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
Y
Duns:
153865951
Principal Investigator:
Anya Asanbaeva
Director
(310) 320-3088
psproposals@poc.com
Business Contact:
Gordon Drew
Chief Financial Officer
(310) 320-3088
gedrew@poc.com
Research Institution:
n/a
Abstract
Development of readily forward-deployable therapeutic measures to enhance wound healing and skin graft survival could promote earlier restoration to health and return to duty. To address the Army"s need for a topical wound treatment with recombinant heat shock proteins (rHSPs) that can be applied to wounds to promote wound healing and skin graft survival, Physical Optics Corporation (POC) proposes to develop a new topical soft tissue treatment (TOSTT) technology. The applied TOSTT releases rHSPs into the extracellular compartment of the wound where they come into direct contact with cellular components essential to the repair process. Development of TOSTT may enhance healing and skin graft survival for complex wounds caused by injury or disease. In Phase I, POC developed the formulation and demonstrated its efficacy to accelerate wound healing and extend skin graft survival in pilot animal studies. In Phase II, further therapeutic evaluation and elucidation of the mechanism of TOSTT"s action on extended skin graft survival in in vivo murine and porcine models as well as an in vitro human skin model will be performed.

* information listed above is at the time of submission.

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