Biodegradable Chitosan Gel Intracavitary Hemostatic Agent

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-09-C-0052
Agency Tracking Number: A2-3978
Amount: $729,996.00
Phase: Phase II
Program: SBIR
Awards Year: 2010
Solicitation Year: 2008
Solicitation Topic Code: A08-176
Solicitation Number: 2008.3
Small Business Information
1 Riverside Circle, Suite 400, Roanoke, VA, -
DUNS: 627132913
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Michael Danilich
 Principal Investigator
 (434) 220-0159
Business Contact
 Maggie Hudson
Title: Contracts Administrator
Phone: (434) 483-4254
Research Institution
Hemorrhage is the leading cause of death from battlefield trauma. Approximately 80% of hemorrhagic deaths on the battlefield are due to intracavitary hemorrhage that is not accessible to direct pressure. Noncompressible hemorrhage is also a primary cause of death in civilian trauma. Unfortunately, methods available to first responders to control hemorrhage are only useful for extremity or superficial truncal injuries and the only viable treatment for intracavitary hemorrhage is surgical intervention. Luna Innovations is developing a novel hemostatic agent and delivery system specifically designed for battlefield treatment of noncompressible intracavitary hemorrhage. The hemostatic agent consists of low-viscosity liquids that rapidly expand into a blood and tissue compatible, non-toxic, bioadhesive and biodegradable gel upon delivery. The product will adhere to and seal injured tissue while promoting hemostasis via several simultaneous mechanisms. The multiple mechanisms, coupled with the sealant nature of the gel, will guarantee hemostasis even in cases of coagulopathy brought on by trauma or fluid resuscitation. The delivery system will be small, lightweight, sterile, preloaded with agent, and easy to use with minimal training on wounds of various sizes and depths.

* Information listed above is at the time of submission. *

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