Biodegradable Chitosan Gel Intracavitary Hemostatic Agent

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$729,996.00
Award Year:
2010
Program:
SBIR
Phase:
Phase II
Contract:
W81XWH-09-C-0052
Award Id:
92025
Agency Tracking Number:
A2-3978
Solicitation Year:
2008
Solicitation Topic Code:
A08-176
Solicitation Number:
2008.3
Small Business Information
1 Riverside Circle, Suite 400, Roanoke, VA, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
627132913
Principal Investigator:
MichaelDanilich
Principal Investigator
(434) 220-0159
submissions305@lunainnovations.com
Business Contact:
MaggieHudson
Contracts Administrator
(434) 483-4254
submissions@lunainnovations.com
Research Institute:
n/a
Abstract
Hemorrhage is the leading cause of death from battlefield trauma. Approximately 80% of hemorrhagic deaths on the battlefield are due to intracavitary hemorrhage that is not accessible to direct pressure. Noncompressible hemorrhage is also a primary cause of death in civilian trauma. Unfortunately, methods available to first responders to control hemorrhage are only useful for extremity or superficial truncal injuries and the only viable treatment for intracavitary hemorrhage is surgical intervention. Luna Innovations is developing a novel hemostatic agent and delivery system specifically designed for battlefield treatment of noncompressible intracavitary hemorrhage. The hemostatic agent consists of low-viscosity liquids that rapidly expand into a blood and tissue compatible, non-toxic, bioadhesive and biodegradable gel upon delivery. The product will adhere to and seal injured tissue while promoting hemostasis via several simultaneous mechanisms. The multiple mechanisms, coupled with the sealant nature of the gel, will guarantee hemostasis even in cases of coagulopathy brought on by trauma or fluid resuscitation. The delivery system will be small, lightweight, sterile, preloaded with agent, and easy to use with minimal training on wounds of various sizes and depths.

* information listed above is at the time of submission.

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