Development of a hand-held, field-deployable multiplex assay for the detection of Chikungunya Virus (CHIKV), West Nile Virus (WNV), and Dengue Virus i

Award Information
Agency:
Department of Defense
Branch
Office of the Secretary of Defense
Amount:
$99,665.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-10-C-0181
Award Id:
96882
Agency Tracking Number:
O093-H20-3139
Solicitation Year:
n/a
Solicitation Topic Code:
OSD 09-H20
Solicitation Number:
n/a
Small Business Information
562 1st Ave S, Suite 600, Seattle, WA, 98104
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
004006628
Principal Investigator:
RaymondHoughton
Director New Product Development
(206) 344-5821
raymond@inbios.com
Business Contact:
EstelaRaychaudhuri
President
(206) 344-5821
inbios@aol.com
Research Institute:
n/a
Abstract
Chikungunya an alphavirus, and the West Nile and Dengue Flaviviruses are carried by mosquitoes. While all three initially lead to febrile illness the subsequent clinical outcomes are very different and in some cases dual infections can occur. All three viruses have the potential to lead to fatal outcomes. Knowledge of the particular viruses carried by mosquitoes in areas of troop deployment would lead to improved and potentially early intervention in military personnel presenting with febrile illness. The purpose of this proposal is to develop a Multiline Lateral flow Immunoassay that would be field deployable and capable of independently detecting the presence of Chikungunya, Dengue or West Nile Viruses directly in mosquitoes. The test would be based on the use of specific antibodies to viral antigens in capture immunoassays. It is anticipated the test will use a colloidal gold detection system. The test will be designed to be stable and field deployable. The availability of such a test would have both military applications in many troop deployment areas as well as utility by epidemiologists in countries where these viral diseases are prevalent.

* information listed above is at the time of submission.

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