A Novel Approach to the Treatment of Cardiac Arrhythmia: A Robotic Catheter for E

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$1,080,190.00
Award Year:
2010
Program:
SBIR
Phase:
Phase II
Contract:
2R44HL095227-02
Agency Tracking Number:
HL095227
Solicitation Year:
2010
Solicitation Topic Code:
NHLBI
Solicitation Number:
PHS2010-2
Small Business Information
LIFESCITECH, LLC
LIFESCITECH, LLC, Box 13714, RESEARCH TRIANGLE PARK, NC, -
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
809789915
Principal Investigator:
SHAPHAN JERNIGAN
() -
Business Contact:
KAREN LEVERT
(919) 941-6080
klevert@setechinv.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): The primary objective of this Phase II research is to design, fabricate, and surgically evaluate a robotic catheter for endocardial ablation procedures. Phase I research successfully demonstrated the feasibility of this concept through the development of a tele-operated catheter prototype with shape memory alloy (SMA) actuated bending segments. Phase II research will build upon the achievements of Phase I to produce a catheter with full ablation capabilities, enhanced maneuverability, computer-controlled ablation modes, and contact stability during ablative energy application. This technology has the potential to transform ablation procedures by providing unprecedented access and maneuverability to open spaces within the heart. Cardiovascular disease is rapidly becoming a worldwide epidemic, claiming more lives in the United States each year than the next six causes of death combined. As the treatment of cardiovascular disease transitions toward minimally-invasive approaches, many procedures now utilize catheters for quick and easy access to intracardiac anatomy. While catheters have proven effective in a number of endovascular procedures (angioplasty, stent deployment, AV node ablation, etc.), their effectiveness in navigating open spaces inside the heart is limited. The development of SMA-actuated robotic catheters will be an enabling technology for such procedures. In Phase I, our multidisciplinary research team (consisting of engineers, surgeons, electrophysiologists, and industrial collaborators) developed a robotic catheter prototype with dual bending segments and promising capabilities. This tele-operated device uses computer- based controls to interpret joystick commands and to actuate the SMA tendons for accurate tracking of the commanded tip position. This prototype exhibits high mobility and precise positioning of the catheter tip, two desirable attributes of ablation catheter technology. The successful refinement of this technology will significantly enhance the efficacy of endocardial ablation procedures. The proposed research will also advance scientific knowledge and understanding of SMA-actuated surgical technologies. It is anticipated that the robotic catheter will be a lower-cost alternative to other robotic surgical systems, making it more accessible to patients and reducing overall healthcare costs. PUBLIC HEALTH RELEVANCE: A novel internally actuated robotic catheter will be developed for endocardial ablation procedures. This technology has the potential to transform ablation procedures by providing unprecedented access and maneuverability to open spaces within the heart. This catheter will be a lower-cost alternative to other robotic surgical systems, making it more accessible to patients and reducing overall healthcare costs.

* information listed above is at the time of submission.

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