Integrated, self-actuated, blood collection and biomarker purification device

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$149,825.00
Award Year:
2013
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-13-C-0051
Award Id:
n/a
Agency Tracking Number:
D122-003-0115
Solicitation Year:
2012
Solicitation Topic Code:
SB122-003
Solicitation Number:
2012.2
Small Business Information
723 Jenifer St, Apt #3, Madison, WI, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
078431936
Principal Investigator:
ErwinBerthier
President
(608) 556-7606
erwin.berthier@gmail.com
Business Contact:
ErwinBerthier
President
(608) 556-7606
erwinberthier@tassoinc.com
Research Institute:
n/a
Abstract
Blood-based assays require upstream mechanisms to acquire sample from a patient, extract the analyte of interest, and preserve the analyte until it can be quantified. Current point-of-care assays overwhelmingly rely on lancet puncture, which is inconvenient because of the presence of blood that is open to the environment and induces high levels of user error inherent with the multiple steps required. In order to develop a platform that can be used in any situation (i.e. low resource setting, moving vehicle) and by an untrained user, we propose the development of a blood collection and sample purification platform integrated in a simple device that does not require complex fluid transfer steps. The technology proposed will allow accessible blood collection and high-purity extraction from the sample collected of a broad range of biomarkers such as viral particles, protein, RNA and DNA for downstream quantification and analysis. The disposable testing platform can be readily interfaced with components for in-the-field testing, or used for stabilizing the biomarkers of interest for safely shipping to a remote laboratory for analysis.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government