Integrated, self-actuated, blood collection and biomarker purification device

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$149,825.00
Award Year:
2013
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-13-C-0051
Agency Tracking Number:
D122-003-0115
Solicitation Year:
2012
Solicitation Topic Code:
SB122-003
Solicitation Number:
2012.2
Small Business Information
Tasso, Inc
723 Jenifer St, Apt #3, Madison, WI, -
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
078431936
Principal Investigator:
Erwin Berthier
President
(608) 556-7606
erwin.berthier@gmail.com
Business Contact:
Erwin Berthier
President
(608) 556-7606
erwinberthier@tassoinc.com
Research Institution:
n/a
Abstract
Blood-based assays require upstream mechanisms to acquire sample from a patient, extract the analyte of interest, and preserve the analyte until it can be quantified. Current point-of-care assays overwhelmingly rely on lancet puncture, which is inconvenient because of the presence of blood that is open to the environment and induces high levels of user error inherent with the multiple steps required. In order to develop a platform that can be used in any situation (i.e. low resource setting, moving vehicle) and by an untrained user, we propose the development of a blood collection and sample purification platform integrated in a simple device that does not require complex fluid transfer steps. The technology proposed will allow accessible blood collection and high-purity extraction from the sample collected of a broad range of biomarkers such as viral particles, protein, RNA and DNA for downstream quantification and analysis. The disposable testing platform can be readily interfaced with components for in-the-field testing, or used for stabilizing the biomarkers of interest for safely shipping to a remote laboratory for analysis.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government