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Surface Enhanced Raman Scattering-Based Oxytocin Quantitation

Award Information
Agency: Department of Defense
Branch: Defense Advanced Research Projects Agency
Contract: W31P4Q-14-C-0028
Agency Tracking Number: D132-001-0022
Amount: $148,155.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: SB132-001
Solicitation Number: 2013.2
Timeline
Solicitation Year: 2013
Award Year: 2013
Award Start Date (Proposal Award Date): 2013-10-29
Award End Date (Contract End Date): 2014-08-01
Small Business Information
256 Midline Rd, Slaterville Springs, NY, -
DUNS: 078861438
HUBZone Owned: Y
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Joel Tabb
 Chief Executive Officer
 (607) 351-2647
 j.tabb@ionicasci.com
Business Contact
 Omar Green
Title: Chief Scientific Officer
Phone: (626) 676-3076
Email: o.green@ionicasci.com
Research Institution
 Stub
Abstract
The ability to readily and rapidly detect the concentration of the 9- and 12-amino acid oxytocin analogs will significantly enhance the efficacy of understanding the conditions under which oxytocin is employed by the body. Ionica Sciences will take advantage of recent miniaturization of highly sensitive instrumentation that allows field application of surface enhanced Raman scattering (SERS), a spectroscopic method that demonstrates exquisite sensitivity. This approach has the twin advantages of significant signal amplification and narrow spectral features, facilitating the identification of multiple target analytes within a single mixture. Using aptamer-modified nanoparticles to differentiate the two forms of oxytocin, which have served as the basis for numerous detection and quantitation methods for biological targets, we will capture and quantitate the target molecules using spectroscopic features unique to it. The modular format of this system will allow for it to be readily adapted for a wide range of pharmaceuticals, hormones, and other small molecule targets.

* Information listed above is at the time of submission. *

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