High Throughput Screening for Advanced Scintillation Detectors

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44RR021986-02
Agency Tracking Number: RR021986
Amount: $740,641.00
Phase: Phase II
Program: SBIR
Awards Year: 2010
Solicitation Year: 2010
Solicitation Topic Code: NCRR
Solicitation Number: PHS2010-2
Small Business Information
DUNS: 123788221
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: Y
Principal Investigator
 (510) 651-1329
Business Contact
Phone: (510) 651-1329
Email: priti@sun-innovations.com
Research Institution
DESCRIPTION (provided by applicant): The objective of this SBIR project is to rapidly discover advanced scintillators for applications in many medical imaging detectors, using an efficient combinatorial screening process. In Phase I, we have developed and demonstrated the feasibility on a set of novel combinatorial screening tools, to rapidly synthesize large collection of scintillators in miniature forms, which accurately reproduced the crystalline phases of many well-known scintillators. In Phase II project, the unique set of efficient scintillator RandD tools will be broadly applied to search for advanced Cerium activated heavy metal oxides and halides scintillators. With the set of combinatorial scintillator tools, at least 12,000 different oxides and halides scintillators will be synthesized and characterized in the 2 year project. The specific aim is to discover a new single crystal scintillator phase with superior luminosity, faster fluorescent decay time, and lower material cost than state-of-the-art medical detector scintillator, e.g. Lu2SiO5:Ce3+. PUBLIC HEALTH RELEVANCE: Scintillator is a key detector material being used in many major medical diagnosis systems, including radiography, mammography, angiography, cardiovascular and fluoroscopic imaging, computed tomography, single photon emission computed tomography, positron emission tomography, etc. The performance of these medical systems, to a large extent, depends on the properties of scintillators, for example, scintillators with higher luminosity results in more sensitive and accurate detection of diseases at early stages which could save lives. Advanced scintillators that will be discovered in the project will significantly improve many medical imaging detectors.

* Information listed above is at the time of submission. *

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