You are here


Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43NS082109-01A1
Agency Tracking Number: R43NS082109
Amount: $516,375.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NINDS
Solicitation Number: PA12-088
Solicitation Year: 2013
Award Year: 2013
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
United States
DUNS: 557510625
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (216) 791-6720
Business Contact
Phone: (216) 619-5915
Research Institution

DESCRIPTION (provided by applicant): Patient motion is a major issue in nuclear medicine imaging studies due to the substantial time to acquire enough counts to produce clinical-quality images. Motion correction algorithms exist but have limited accuracy and effectiveness, and in many instances the only practical alternative is to re-scan the patient. Most work on patient motion sensing has focused on optical tracking systems. Although sub-millimeter accuracy has been attained in research laboratories, thecost, complexity, and line-of-sight requirement of external optical tracking systems have prevented their routine use in clinical nuclear medicine departments. There is an unmet clinical need for a practical and inexpensive patient motion sensing device for nuclear medicine studies. This is especially true for brain PET and SPECT studies which demand high resolution and accurate quantification, both of which may be severely degraded by patient motion. We propose a novel and inexpensive method for head tracking for brain PET and SPECT studies that satisfies these practical requirements. Our aims in phase I are to develop the necessary hardware and software for accurate head motion sensing and to validate this method in clinical brain PET and SPECT studies.PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE: We propose to develop and evaluate a novel and inexpensive motion sensing device for head tracking during brain PET and SPECT studies. Patient motion often limits image quality, and there is an unmet clinical need for an inexpensive head tracking solution that is practical for clinical nuclear medicine departments. The data from this study will demonstrate the feasibility of our approach and will guide future clinical research in motion compensationfor higher resolution and more accurate quantification in brain PET and SPECT imaging.

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government