Bacteriophages for reducing Vibrio tubiashii associated mortality of shellfish

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$99,991.00
Award Year:
2013
Program:
SBIR
Phase:
Phase I
Contract:
2013-00319
Agency Tracking Number:
2013-00319
Solicitation Year:
2013
Solicitation Topic Code:
8.7
Solicitation Number:
USDA-NIFA-SBIR-003848
Small Business Information
INTRALYTIX INC
351 W CAMDEN ST STE 100, Baltimore, MD, 21201-8603
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
005318758
Principal Investigator:
Alexander Sulakvelidze
Chief Scientist
(410) 625-2533
asulakvelidze@intralytix.com
Business Contact:
John Woloszyn
President and CEO
(410) 625-3813
jwoloszyn@intralytix.com
Research Institution:
Stub




Abstract
This project aims to develop a phage-based product (VTP-100) that will contain a mixture of lytic phages effective against a variety of hatchery strains of Vibrio tubiashii. V. tubiashii is a major cause of larval shellfish mortality, which results in increased costs to the aquaculture industry and consumer. Therefore, if our V. tubiashii phage preparation is successfully commercialized, its use could have a very significant impact on reducing larval mortality in hatcheries and, potentially, on reducing the cost of producing and buying oysters. On a more general level, if the results of the studies proposed in this application support our idea that lytic phages may be effective in managing V. tubiashii-associated mortality of oyster larvae, the same platform technology could be used to develop similar phage-based products against other bacterial pathogens of concern to the aquaculture industry. The studies proposed in the present Phase I SBIR application are designed to conduct research required to obtain data critical for our subsequent development and commercialization of VTP-100. Phase I SBIR funding will be critical for conducting research with our V. tubiashii bacteriophages, which will provide a foundation for our subsequent Phase II SBIR R & D efforts and for obtaining regulatory approvals and aiding the product's commercialization.

* information listed above is at the time of submission.

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