SBIR Phase I: Biotransformable Block Terpolymers for Drug-Eluting Stents

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$100,000.00
Award Year:
2007
Program:
SBIR
Phase:
Phase I
Contract:
0712489
Award Id:
84818
Agency Tracking Number:
0712489
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
518 N. Main Street, # 286, Hattiesburg, MS, 39401
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
788730542
Principal Investigator:
Lisa Kemp
PhD
(601) 347-2811
lisa.kemp@ablitech.com
Business Contact:
Lisa Kemp
PhD
(601) 347-2811
lisa.kemp@ablitech.com
Research Institution:
n/a
Abstract
This Small Business Innovation Research (SBIR) Phase I research research project aims to develop a polymer system for drug eluting coronary stents (DES). The material is expected to provide higher drug loading with a controlled drug release profile, as well as tunable mechanical properties over the lifetime of the stent. This will be accomplished using block terpolymers of specific composition to which drug molecules will be covalently attached. Recent advances in DES technology have increased the success rate of CHD treatment; however, restenosis (re-blockage of the artery through the stent) occurs in 10% of the implanted stents. Also currently available drug eluting coatings deliver the bulk of the loaded drug within the first 48 hours of stent placement, with little to no delivery after 30 days. Thus a new type of stent that can overcome the limitations of current stents would be of significant value.

* information listed above is at the time of submission.

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