SBIR Phase I: Compact NMR for Dilute Pathogen Detection

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$99,729.00
Award Year:
2008
Program:
SBIR
Phase:
Phase I
Contract:
0810791
Award Id:
88431
Agency Tracking Number:
0810791
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
2301 Yale Blvd. SE, Suite C-2, Albuquerque, NM, 87106
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
362518149
Principal Investigator:
Eiichi Fukushima
PhD
(505) 244-0017
eiichi@abqmr.com
Business Contact:
Eiichi Fukushima
PhD
(505) 244-0017
eiichi@abqmr.com
Research Institute:
n/a
Abstract
This Small Business Innovation Research Phase I project develops compact NMR devices for rapid detection of dilute cells and pathogens to replace blood culture, providing improvements in detection speed and sensitivity while decreasing cost. They will enhance medical care and address the growing crisis of sepsis in hospitals. The devices are based on a combination of technologies - microcoil NMR and biochemical labeling by magnetic nanoparticles. The research will extend the performance boundaries of this technology, resulting in a detector for extremely dilute, immuno-magnetically labeled, pathogens. The broader impacts of this research are based on the importance of early detection of dilute concentration of pathogens and other cells that would permit more timely diagnosis of diseases, thereby enhancing healthcare outcomes. Early detection also reduces costs, as patients recover faster and require less intervention. Blood culture is a workhorse of the diagnostic lab, so there is a demand for a device that substantially improves its performance. Sepsis is a growing public health problem with significant consequences, so the motivation to adopt new tools for the detection and treatment of this condition is strong. The NMR device proposed here achieves enhanced performance in sensitivity, speed, size, and cost that will permit new uses in the future, including in the primary care setting and in the field.

* information listed above is at the time of submission.

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