AUDITORY BRAINSTEM RESPONSE AT HIGH STIMULUS RATES

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$495,783.00
Award Year:
1990
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
11196
Agency Tracking Number:
11196
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
100 Bush St 26th Floor, San Francisco, CA, 94104
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
THE GOAL OF THIS RESEARCH IS TO IMPLEMENT AND TEST AN ALGORITHM THAT WILL PERMIT ACCURATE RECORDING OF THE AUDITORY BRAINSTEM RESPONSE (ABR) AT VERY HIGH-REPETITION RATES BY EXTRACTING THE ABR FROM LATER RESPONSES (E.G., THE MIDDLE LATENCY RESPONSE). PHASE I WILL ACCOMPLISH THE GOAL OF PROGRAMMING THE NECESSARY STIMULUS AND ANALYSIS ALGORITHMS, AND WILL TEST THE METHOD UNDER CONDITIONS OF REAL NOISE AND JITTER BY ANALYZING ABR RECORDINGS FROM ANESTHETIZED LABORATORY CATS. PHASE II WILL STUDY THE USE OF THE METHOD IN RECORDINGS FROM HUMANS, USING A VARIETY OF FILTER SETTINGS AND THREE OR MORE SIMULTANEOUS CHANNELS. THE IMPROVED METHOD OF RECORDING THE ABR WILL INCREASE THE SENSITIVITY OF ABR TESTING IN A WIDE VARIETY OF DISEASES, INCLUDING HIV INFECTION AND AIDS.

* information listed above is at the time of submission.

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