Source Localization Head Shapes from External Measures

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,992.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 MH52492-01A1,
Award Id:
29581
Agency Tracking Number:
29581
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
475 Gate 5 Road, Suite 255, Sausalito, CA, 94965
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Don Jewett
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
Our goal is to develop external head shape/skull parameter measurement techniques which will permitconstruction of Boundary Element Method (BEM) head shape models to improve Dipole Source Localizatioprocedures, useful in analyzing brain Event-Related Potentials (ERPs) and magnetoencephalograms (MEGtechniques would make electrophysiological imaging a potentially useful research and clinical tool wwide variety of human brain functions that are testable with cognitive-based ERPs as well as with seresponses from lower brain centers. In turn, this could affect diagnosis and/or treatment evaluationin schizophrenics, depressives, drug abusers, and Alzheimer's patients, among others. The Specific Ato develop the necessary techniques for a scalp-derived headshape-model and then compare the DSL resmodel, with a gold standard model constructed when additional detail of inner surfaces from the MRIComparisons will include both simulations and analysis of evoked response data.

* information listed above is at the time of submission.

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