Development of Monoclonal and Polyclonal Antibodies Suitable for a Commercial Perfluorooctanoic Acid (PFOA) ELISA

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$79,892.00
Award Year:
2006
Program:
SBIR
Phase:
Phase I
Contract:
2006-33610-16767
Award Id:
80939
Agency Tracking Number:
2006-00220
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
54 Steamwhistle Drive, Warminster, PA, 18974
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
FernandoRubio
President
(215) 357-3911
frubio@abraxiskits.com
Business Contact:
FernandoRubio
President
(215) 957-6477
frubio@abraxiskits.com
Research Institute:
n/a
Abstract
Perfluorooctanoic acid (PFOA) is a synthetic chemical which does not occur naturally in the environment,it has been used in many commercial applications. A number of scientific findings since the late 1990's have elevated PFOAs to the category of great environmental concern beacuse of its persistence, and the potential for bioaccumulation and biomagnification. Effective environmental and health protection requires the sensitive and efficient detection of PFOA in various sample matrices such as foods, water, soil, sediment, blood, etc. Therefore, faster and less expensive analytical methods such as ELISA for the detection of PFOA are ideal for the establishment of efficient and cost-effective screening programs for these compounds. The purpose of this project is to develop the immunoreagents (polyclonal and monoclonal antibodies) which react with PFOAs with sufficient selectivity, affinity and avidity to be utilized in the development of a commercial immunoassay system.

* information listed above is at the time of submission.

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