Development of Monoclonal and Polyclonal Antibodies Suitable for a Commercial Perfluorooctanoic Acid (PFOA) ELISA

Award Information
Agency: Department of Agriculture
Branch: N/A
Contract: 2006-33610-16767
Agency Tracking Number: 2006-00220
Amount: $79,892.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Abraxis, LLC
54 Steamwhistle Drive, Warminster, PA, 18974
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Fernando Rubio
 President
 (215) 357-3911
 frubio@abraxiskits.com
Business Contact
 Fernando Rubio
Title: President
Phone: (215) 957-6477
Email: frubio@abraxiskits.com
Research Institution
N/A
Abstract
Perfluorooctanoic acid (PFOA) is a synthetic chemical which does not occur naturally in the environment,it has been used in many commercial applications. A number of scientific findings since the late 1990's have elevated PFOAs to the category of great environmental concern beacuse of its persistence, and the potential for bioaccumulation and biomagnification. Effective environmental and health protection requires the sensitive and efficient detection of PFOA in various sample matrices such as foods, water, soil, sediment, blood, etc. Therefore, faster and less expensive analytical methods such as ELISA for the detection of PFOA are ideal for the establishment of efficient and cost-effective screening programs for these compounds. The purpose of this project is to develop the immunoreagents (polyclonal and monoclonal antibodies) which react with PFOAs with sufficient selectivity, affinity and avidity to be utilized in the development of a commercial immunoassay system.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government