CHIMERIC YF/DEN2 AS A VACCINE CANDIDATE FOR DENGUE VIRUS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$104,504.00
Award Year:
1999
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
1R43AI044565-01
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
ACAMBIS, INC.
38 SIDNEY ST, 4TH FL, CAMBRIDGE, MA, 02139
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
FARSHAD GUIRAKHOO
() -
Business Contact:
(617) 494-1339
LGORDON@ORAVAX.COM
Research Institution:
n/a
Abstract
Not Available MSE Technology Applications, Inc. (MSE), with United Technologies Research Center and HyperTech Concepts Company proposes to develop combine propulsion for a small reusable launch vehicle (RLV), known as the KLINtm Cycle, consisting of a thermally integrated deeply cooled turbojet and liquid rocket engine. The objective of this approach is to achieve a high pressure ratio in a simple, lightweight turbojet engine. The result is an exceptional engine thrust-to-weight ratio and improved specific impulse and mass fraction of the launcher. For a heavy launcher, the KLINtm Cycle promises RLV gross takeoff weight (GTOW) reduction by a factor of two with prospects of lower dry weight. If based on the FL-10 engine family, the KLINtm Cycle makes a small single-stage-to-orbit and two-stage-to-orbit RLV feasible and economically very attractive. Specific objectives of the initial portion of the study are to demonstrate: 1) the performance and mass of a KLINtm Cycle based on an existing rocket engine of the RL-10 family applied to a small RLV; 2) the advantages of integrating a KLINtm Cycle into a small RLV (50-100 ton of GTOW); 3) the core technology development program. The benefit to the Air Force is low life-cycle cost combined propulsion for a space plan which can double existing rocket propulsion capabilities by the year 2010.

* information listed above is at the time of submission.

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