High Spatial Resolution Ultrafast Sum-Frequency Generation Microscope

Award Information
Agency:
Department of Energy
Branch
n/a
Amount:
$149,996.72
Award Year:
2014
Program:
STTR
Phase:
Phase I
Contract:
DE-SC0011365
Award Id:
n/a
Agency Tracking Number:
210212
Solicitation Year:
2014
Solicitation Topic Code:
07a
Solicitation Number:
DE-FOA-0000969
Small Business Information
1665 E. 18th Street, Suite 112, Tucson, AZ, 85719-6808
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
058268652
Principal Investigator:
Alexander McCourt
Dr.
(520) 903-2345
amccourt@physics-math.com
Business Contact:
Kevin Kremeyer
Dr.
(520) 882-7349
kremeyer@physics-math.com
Research Institution:
University of California, Irvine (UCI)

Natural Sciences II
Irvine, CA, 92697-1075
() -
Nonprofit college or university
Abstract
Vibrationally resonant sum-frequency generation (SFG) spectroscopy is a second order nonlinear optical technique that features high chemical selectivity and a set of selection rules that makes it an ideal complement to coherent Raman scattering (CRS) as an imaging tool. Attempts have been made to construct high-resolution, high speed SFG microscopes, but to date both the resolving power and image acquisition speed have been limited to unacceptable ranges due to the lack of purely refractive optical elements capable of operating without deleterious chromatic effects over the wavelengths of the two beams used to produce SFG in samples. In order to increase both the spatial resolution and the scanning speed of SFG microscopes, we will design custom achromatic optical elements for operation at wavelengths in the near- and mid-infrared regions. Additionally, we use these improvements to incorporate both CRS and second harmonic generation into the microscope. Commercial Applications and Other Benefits: The proposed technology will introduce a microscope that will greatly enhance researchers ability to image fragile and sensitive materials without the use of exogenous agents. Examples include biological tissues, works of art and ancient objects of archeological significance. In particular, a multimodal microscope incorporating SFG and CRS will provide researchers with the ability to image biological tissue structure that cannot be currently imaged without labels or destructive methods. Such a microscope could profoundly affect fields of study such as medicine and biomechanical engineering.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government