Technology to Regulate Circadian Rhythm for Health and Performance

Technology to Regulate Circadian Rhythm for Health and Performance

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-14-P-0047
Agency Tracking Number: A14A-009-0202
Amount: $149,837.00
Phase: Phase I
Program: STTR
Awards Year: 2014
Solicitation Year: 2014
Solicitation Topic Code: A14A-T009
Solicitation Number: 2014.A
Small Business Information
15150 North Hayden Road, Suite 106, Scottsdale, AZ, -
DUNS: 182166616
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Sung Lee
 Director of Research
 (480) 588-6840
 sung.lee@brainstatetech.com
Business Contact
 Lee Gerdes
Title: CEO
Phone: (480) 588-6840
Email: lee.gerdes@brainstatetech.com
Research Institution
 Wake Forest School of Medicine
 Charles T M.D.
 Charles Tegeler, M.D.
Medical School Center Blvd
Winston-Salem, NC, 27157-
 (336) 716-9482
 Nonprofit college or university
Abstract
We propose a wearable, dual-use neurotechnology device. The Personal Brainwave Headband, driven by tablet or smartphone, is designed for noninvasive closed-loop acoustic stimulation, to permit improved circadian regulation. It will measure brain electrical activity from scalp overlying four key sectors of cortex, perform high-resolution spectral analysis of the signals, and use software algorithms to translate dominant brain frequencies into audible tones of changing pitch and timing. Resonance between brainwaves and audible tones facilitates self-optimization, manifesting as greater left-right hemispheric symmetry and more optimized ratios of energy between low and high frequencies of brain electrical activity. The net result of brain self-optimization will be more restful sleep. Preliminary data demonstrate efficacy of the approach when using external amplifiers and a laptop computer configuration, to support symptom reduction in insomnia, PTSD, TBI, and other conditions. The device will also have functionality for regular use in a monitor-only mode to enable identification of brain states associated with vulnerability (BSAV"s). BSAV"s (to be studied in Phase II) are those brain activity patterns (combinations of asymmetry and suboptimal ratios of energy between low and high frequencies) that are associated with a higher likelihood of experiencing emotional disturbance, or demonstrating compromised performance or maladaptive behavior.

* Information listed above is at the time of submission. *

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