Non Invasive Assessment of Intracranial Pressure and Cerebrovascular Status after Traumatic Brain Injury

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$99,643.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-09-C-0125
Agency Tracking Number:
O091-H02-3035
Solicitation Year:
2009
Solicitation Topic Code:
OSD09-H02
Solicitation Number:
2009.1
Small Business Information
Active Signal Technologies, Inc.
Hammonds South, Unit Q, 611 North Hammonds Ferry Road, Linthicum Heights, MD, 21090
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
959989054
Principal Investigator:
John Sewell
Principal Design Engineer
(717) 235-9238
sewellactv@verizon.net
Business Contact:
Arthur Cooke
President
(410) 636-9350
arthur@activesignaltech.com
Research Institution:
n/a
Abstract
Given the critical need for early detection of TBI and the potentially associated increase in ICP a requirement exists for a system capable of detecting elevated ICP and TBI, especially cerebrovascular status. The requirement is for a combination small, portable, robust fieldable system, and this response to that requirement is a combination of non-invasive acoustic techniques for determining elevated ICP as well as cerebrovascular status. One system, the Brain Acoustic Monitor, is based on an active stimulation of skull resonance features along with a passive monitoring of arterial response to determine elevated ICP and cerebrovascular anomalies. The other, cochlear microphonic potential (CM), determines the degree of ICP increase. Both approaches have been evaluated against calibrated ICP monitors in one case human subject and the other animal studies. Phase I will combine the systems to detect both elevated ICP as well as set forth a method to approximate a real value. This in anticipation of Phase II where the system will be evaluated against invasive ICP monitors, TCD, and CTA, prior to a final system integration.

* information listed above is at the time of submission.

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