You are here

ChemoFilter: A Novel Catheter Device to Enable High-Dose Chemotherapy Treatment

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41CA183327-01
Agency Tracking Number: R41CA183327
Amount: $224,999.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NCI
Solicitation Number: PA13-089
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
645 WOODSTOCK RD
BURLINGAME, CA 94010-6874
United States
DUNS: 78769813
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 ANAND PATEL
 (630) 301-0513
 chemofilterinc@gmail.com
Business Contact
 ANAND PATEL
Phone: (630) 301-0513
Email: anand.patel.05@gmail.com
Research Institution
 UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
 
UNIVERSITY OF CALIFORNIA SAN FRANCISCO 3333 California Street., Ste 315
SAN FRANCISCO, CA 94143-0962
United States

 () -
 Nonprofit college or university
Abstract

Project Summary: Intravenous dosing of drugs for applications ranging from cancer chemotherapy to anti-microbials to lytic (blood clot dissolving) agents is limited by systemic toxicity. Currently, the only ways to remove drugs from the blood are throughnatural metabolism or costly impractical measures such as dialysis. Despite intense focus on targeted drug delivery agents, these therapies are costly and rare, especially considering traditional older drugs are low-cost yet clinically effective, and can be used in a targeted manner with higher efficacy if they could be filtered out of the body after their effect in order to prevent toxicities. Intra-arterial chemotherapy (IAC) is performed in interventional radiology (IR), enabling direct delivery of chemotherapy to tumors by guiding micro-catheters into the arteries feeding these tumors. IAC with Doxorubicin (Dox) has proven to be a successful method demonstrating mortality benefit in randomized controlled trials (1, 2) for treating non- operative prima

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government