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Development of a Novel Antimicrobial Foley Catheter to Prevent CAUTIs

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41DK102237-01
Agency Tracking Number: R41DK102237
Amount: $224,363.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIDDK
Solicitation Number: PA13-051
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
35 INDUSTRIAL PKWY
BRANCHBURG, NJ 08876-3424
United States
DUNS: 101248508
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 MARTIN VON DYCK
 (908) 722-5000
 mcdyck@hydromer.com
Business Contact
 MARTIN DYCK
Phone: (908) 722-5000
Email: mcdyck@hydromer.com
Research Institution
 BRIGHAM YOUNG UNIVERSITY
 
BRIGHAM YOUNG UNIVERSITY OFFICE OF RESEARCH AND CREATIVE ACTIVITIES A-285 ASB
PROVO, UT 84602-1001
United States

 () -
 Nonprofit college or university
Abstract

DESCRIPTION (provided by applicant): Catheter-associated urinary tract infections (CAUTI) are a leading cause of hospital-acquired infections and lead to increased costs, suffering and mortality. A primary contributor to CAUTI is formation of bacterial biofilms on indwelling catheters. Biofilms are inherently resistant to most antibiotics, and once established serve as a bacterial reservoir propagating infection to other tissues. Elution of antimicrobials from catheter has been recognized as a potential means of preventing biofilm formation on catheters and reducing CAUTI. Silver and nitrofurazone-releasing catheters are currently clinical use. However, catheters releasing these antimicrobials have relatively short durations of activity, prevent biofilm development for several days and are largely ineffective against certain key pathogens. Consequently, there is an unmet need for antimicrobial catheters that prevent biofilm formation for extended periods. Therefore, we propose to develop a novel antimicr

* Information listed above is at the time of submission. *

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