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High Throughput Manufacturing of Monodispersed Nanoparticles for Biomedicine

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41AG050381-01A1
Agency Tracking Number: R41AG050381
Amount: $150,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIA
Solicitation Number: PA14-072
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
104 INWOOD DRIVE
SAN MARCOS, TX 78666-3702
United States
DUNS: 831536615
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 JOHN MASSINGILL
 (512) 557-7461
 JOHN.MASSINGILL@CHEMTOR.COM
Business Contact
 JOHN MASSINGILL
Phone: (512) 557-7461
Email: JOHN.MASSINGILL@CHEMTOR.COM
Research Institution
 TEXAS STATE UNIVERSITY-SAN MARCOS
 
TEXAS STATE UNIVERSITY Sponsored Programs 601 UNIVERSITY DRIVE
SAN MARCOS, TX 78666-4684
United States

 () -
 Nonprofit college or university
Abstract

DESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer (STTR) project focuses on the development of a new platform manufacturing process for large-scale preparation of monodispersed polymeric nanoparticles (NPs) suitable for biomedical applications through the use of a large-scale fiber fluidic system. Although laboratory processes for reproducible synthesis of polymeric particles through emulsion and nanoprecipitation methods have matured, the development of suitable methods for synthesis of such monodispersed NPs in the scales required for commercialization has not been achieved. The proposed system aims to meet this need by providing a versatile, rugged and easily scalable process that can be used for continuous manufacture of polymeric NPs in a small footprint. After seeing our preliminary data, David Nowotnik, Senior Vice President Research and Development at Access Pharmaceuticals wrote: A process that could be used in the lab to make monodisperse nanoparticles for me

* Information listed above is at the time of submission. *

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