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Development of fluorescence-based receptor binding assays for the detection

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41ES023724-01A1
Agency Tracking Number: R41ES023724
Amount: $224,408.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIEHS
Solicitation Number: PA13-235
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
218 MADELINE DR
WILMINGTON, NC 28405-3916
United States
DUNS: 78782502
HUBZone Owned: No
Woman Owned: Yes
Socially and Economically Disadvantaged: No
Principal Investigator
 JENNIFER MCCALL
 (910) 962-2081
 mccalljr@uncw.edu
Business Contact
 JENNIFER MCCALL
Phone: (704) 458-4169
Email: seatoxresearch@gmail.com
Research Institution
 UNIVERSITY OF NORTH CAROLINA WILMINGTON
 
UNIVERSITY OF NORTH CAROLINA WILMINGTON 601 S COLLEGE RD
WILMINGTON, NC 28403-5973
United States

 () -
 Nonprofit college or university
Abstract

DESCRIPTION (provided by applicant): Harmful algal blooms (HABs) are becoming frequent occurrences off the coasts of the United States, particularly in coastal waters of New England, the Gulf of Mexico, and the Pacific Ocean. Historically, HABs have beenassociated with fish kills and marine mammal mortalities; however, their effects on human health and economic loss due to HAB contamination of seafood are becoming more prevalent, with conservative estimates around 82 million annually. The toxic effects of HABs are precipitated by the production of toxins by various species of marine algae and microorganisms, which are then consumed by filter feeding shellfish and finfish. Accumulation in significant quantities can result in toxicity and death in marine animals and humans. Many of the natural toxins produced by marine phytoplankton are heat and acid stable; therefore, cooking contaminated seafood does not eliminate the risk of poisoning. Currently, US state agencies monitor for the presence of toxic p

* Information listed above is at the time of submission. *

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