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Image-guided planning system for skull correction in children with craniosynostos

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41HD081712-01
Agency Tracking Number: R41HD081712
Amount: $224,798.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NICHD
Solicitation Number: PAR13-091
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
28 CORPORATE DRIVE SUITE 204
CLIFTON PARK, NY 12065-8688
United States
DUNS: 10926207
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 MARIUS LINGURARU
 (202) 476-3059
 mlingura@childrensnational.org
Business Contact
 VICKI RAFFERTY
Phone: (518) 371-3971
Email: contracts@kitware.com
Research Institution
 CHILDREN'S RESEARCH INSTITUTE
 
111 MICHIGAN AVENUE NW
WASHINGTON, DC 20010-2916
United States

 () -
 Domestic nonprofit research organization
Abstract

DESCRIPTION (provided by applicant): Craniosynostosis is the premature fusion of cranial sutures and occurs in approximately one in 2000 live births. It results in cranial malformation that can lead to elevated intra-cranial pressure, brain growth impairment, and developmental deficiency. The most common treatment option for craniosynostosis is surgery. Currently, surgical treatment planning of craniosynostosis is mostly qualitative, subjective and irreproducible guided mainly by the surgeon's experience. While virtual planning has been successfully introduced in niche areas of craniofacial surgery, such as corrective jaw surgery applications, clinical tools that provide accurate and reproducible evaluation of cranial morphology to guide cranial vault remodeling do not yet exist. To cover this gap in current clinical practice, we will develop personalized preoperative planning for infants with craniosynostosis that allows for decreased operative time and blood loss, thereby reducing perioperative morbidi

* Information listed above is at the time of submission. *

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