Quasimonochromatic X-Ray Source for Mammography

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$49,968.00
Award Year:
1993
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
22001
Agency Tracking Number:
22001
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Adelphi Technology Inc. (Currently Adelphi Technology, Inc.)
2181 Park Boulevard, Palo Alto, CA, 94306
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Melvin A. Piestrup
(415) 328-7337
Business Contact:
() -
Research Institution:
n/a
Abstract
The objective of the program is to investigate the use of parametric x-ray radiation (PXR) as a tunable, quasimonochromatic x-ray source for mammography. PXR is generated by placing natural, synthetic crystals, or multilayer structures into the path of a relativistic electron beam. The virtual photons associated with the fields of the electrons are Bragg reflected by the periodic crystal lattice and real x-rays appear at the Bragg angle. The production process is, thus, analogous to x-ray diffraction by crystals, except that the x-ray beam incident at the Bragg angle is replaced by a relativistic electron beam. This laser-like source is quasi-monochromatic, directional, easily tunable, and polarizable. Such a source would permit the determination of the optimum photon energy which minimizes dosage and maximizes contrast between tumors and normal breast tissue. We will develop a Monte Carlo simulation of mammography, which will calculate image quality and dosage as a function of the photon energy and bandwidth of our PXR source. We will determine the needed photon flux for mammography that can be obtained from a PXR source. To make the source more practical, we will investigate methods for reducing the needed electron beam energy to below 20 MeV. Experimental confirmation of PXR generation at low to moderate electron beam energies will be attempted using an existing experimental setup.

* information listed above is at the time of submission.

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