The Inflammatory Cell Differential Counter, A New Tool to Combat Mastitis On-Site

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$80,000.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
2004-33610-14369
Award Id:
67108
Agency Tracking Number:
2004-00174
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
21 Davis Drive, Research Triangle Park, NC, 27709
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Rudy Rodriguez
(919) 597-6434
rudy@aadiagnostics.com
Business Contact:
Rudy Rodriguez
Principal
(919) 466-8059
rudy@aadiagnostics.com
Research Institute:
n/a
Abstract
Mastitis, an infection of the milk-producing glands of dairy cows, is a $5 billion problem worldwide. The current, on-site method used to diagnose mastitis, and to monitor its incidence, is to count the total number of "body cells" (white cells and other body cells) present in the milk. There has been little change to this method over the last ten years. Academic studies, conducted with complex instruments, have shown that identifying and counting each of the different white cells, that rise and fall in response to infections, would be a superior method to diagnose and monitor mastitis, and to evaluate udder health. For example, the best indicator of an active bacterial infection is the rise in the number of one specific kind of infection-fighting white cell, known as a "neutrophil" Unfortunately, the complex instruments used in those academic studies are impractical for use in a dairy farm. Advanced Animal Diagnostics proposes to develop an "on site" device, the Inflammatory Cell Differential Counter (ICDC), which (1) has the ability to differentiate infection-fighting inflammatory cells-e.g. neutrophils-from other cells (2) requires minimum operator judgment or training, and (3) is more accurate than existing tools, especially at the early stages of infection. The ICDC takes a digital picture of each cell, which makes it less susceptible to misidentification and other errors. In summary, the ICDC is expected to bring to the farm a level of performance previously available only in a sophisticated laboratory, and yet, is envisioned to be simple, rugged and inexpensive.

* information listed above is at the time of submission.

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