COMPUTERIZED NONINVASIVE MONITORING OF BRAIN OXYGENATION

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$100,000.00
Award Year:
2002
Program:
SBIR
Phase:
Phase I
Contract:
1R43NS042470-01A1
Agency Tracking Number:
NS042470
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
ADVANCED BIOENGINEERING TECHNOLOGIES
ADVANCED BIOENGINEERING TECH, 17 INDIAN ROCK RD, WARREN, NJ, 07059
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JOHN MATONICK
(908) 903-0271
JMATONICK@YAHOO.COM
Business Contact:
JOHN MATONICK
(908) 903-0271
JMATONICK@YAHOO.COM
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): Stroke continues to be the number three principal cause of death, and one of the leading causes of disability, in the United States. Continued improvements in these statistics requires a better understanding of the functional dynamics of the cerebral vasculature and oxygen utilization of the surrounding tissue during various physiological conditions.We propose a computerized method that affords real time continuous noninvasive measurement and quantitative analysis of the combined hemoglobin saturation levels and auditory evoked potentials during ischemic conditions of the brain. Unique enhancements of the current Near Infrared Spectroscopy (NIRS) technology have been developed along with a Brain Auditory Evoked Potential (BAEP) system. In Phase I we will demonstrate the feasibility of such an undertaking with animal experiments designed to investigate the capabilities of the novel NIRS system coupled with the BAEPs generated during varying extents of cerebral ischemia. In Phase II, we will extend this application to further investigate conditions of cerebral ischemia as well as hypoxic states. The long-term goal is to provide a real time noninvasive monitoring capability of brain oxygenation during surgical procedures and cerebral vascular accidents.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government