A Novel Vortex Extractive-Reaction Process for Reducing Organic Wastes Dissolved in Aqueous Streams

Award Information
Agency:
Department of Energy
Branch
n/a
Amount:
$0.00
Award Year:
2002
Program:
SBIR
Phase:
Phase I
Contract:
DE-FG02-01ER83134
Agency Tracking Number:
65668S01-II
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Advanced Cytometry Instrumentation Systems
Baird Research Park, 1576 Sweet Home Road, Amherst, NY, 14228
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Martin Casstevens
(716) 689-9797
casstevens@lptinc.com
Business Contact:
Carleton Stewart
65668
(716) 689-9797
stewarts@rpciflowcytometry.com
Research Institution:
n/a
Abstract
65668 Flow cytometers are established clinical and research tools with application to proteomics, drug discovery, and the fight against bioterrorism. This project will develop several flow cytometer innovations to improve overall efficiency; reduce size, resource requirements, and cost; and, most importantly, permit greater amounts of information to be extracted from each cellular interrogation. Phase I demonstrated the use of modified laser beams to extract complex and previously unattainable spectral information from flow cytometers. A novel collection/detection system was demonstrated that is more efficient, has less components, and is easier to align. In Phase II, the Phase I innovations will be further optimized, tested, and combined into a single advanced prototype. This prototype will be demonstrated with several relevant biochemical models and critically evaluated. A data acquisition system will be designed and built to optimally process the acquired data. Commercial Applications and Other Benefits as described by the awardee: The improved flow cytometers would be used to extract greater amounts of information from complex systems at a reduced cost. Applications are expected in proteomics, drug discovery, clinical research, and biomonitoring, etc.

* information listed above is at the time of submission.

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