Integrated Architecture for Functional Genomic Measurements

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-04-C-0029
Agency Tracking Number: A032-1523
Amount: $729,874.00
Phase: Phase II
Program: SBIR
Awards Year: 2004
Solicitation Year: 2003
Solicitation Topic Code: A03-161
Solicitation Number: 2003.2
Small Business Information
400-1 Totten Pond Road, Waltham, MA, 02451
DUNS: 009182267
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Roland Carel
 Senior Systems Architect
 (781) 890-4440
Business Contact
 Richard Dweck
Title: CEO and Founder
Phone: (781) 890-4440
Research Institution
Successful use of microarray technology for the investigation of biological systems requires an integrated informatics infrastructure. The objective of this research and development effort is to specify such an integrated informatics architecture to support biological research and discovery efforts being conducted throughout the Department of Defense's (DoD) Medical Research and Materiel Command (MRMC). This next generation integrated architecture, when implemented, will dramatically improve research quality and decrease time to biological discovery. No existing commercial solution provides as complete or as integrated a solution for the advanced analysis of array functional genomic measurements as the one defined here. Current commercial or academic solutions are mostly limited to basic analysis of array data to determine differential expression and do not practically address the advanced analysis of array data to uncover sets of associations between genes. Most of these solutions require scientists to spend their time tediously feeding data from one analytical or visualization component to the next to complete data analyses. Moreover, no commercial solutions exist to assist scientists in the critically important task of assembling testable models from the results of these advanced analyses. The architecture specified in this report overcomes all of these deficiencies.

* Information listed above is at the time of submission. *

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