Ambulatory Real Time High Channel Count Electroencephalograph

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$908,531.00
Award Year:
2007
Program:
SBIR
Phase:
Phase II
Contract:
2R44NS053129-02
Agency Tracking Number:
NS053129
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
ADVANCED MEDICAL ELECTRONICS CORPORATION
6901 EAST FISH LAKE ROAD, SUITE #190, MAPLE GROVE, MN, 55369
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
927303412
Principal Investigator:
PAUL GIBSON
(763) 463-4814
PGIBSON@AME-CORP.COM
Business Contact:
TOM HENDRICKSON
() -
thendrickson@ame-corp.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): A new wireless network standard called Ultra-Wideband (UWB) makes possible the creation of an ambulatory electroencephalograph (EEG) instrument that can transmit 160 full-bandwidth (DC to 7.5 kHz) channels or 256 clinic al bandwidth channels in real time. It will be designed with modular amplifiers that allow either a low noise clinical bandwidth or an enhanced wide bandwidth. It will be comparatively evaluated in human tests against a tethered system. The developed UWB w ireless system will be suitable for applications such as high channel count scalp EEG, cortical grid electrodes, multi-contact depth electrodes, and fine wire microelectrodes for multi-single-unit recording. The proposed UWB wireless EEG system will make p ossible for the first time recording single neuron extra-cellular action potential (AP) and local field potential (LFP) from freely behaving and seizing humans. It will also remove restrictions imposed on patient movement and susceptibilities to artifact f rom movement caused by a tethered system. Ultra-wideband (UWB) is a fast emerging radio technology with the potential for major advances in wireless communications. The UWB standard is officially designated IEEE 802.15.3a. The utilization of large bandwidt h allows UWB to transmit large amounts of data. One of the most common neurological diseases is epilepsy. Epilepsy refers to the tendency to have unprovoked seizures, and encompasses a number of different syndromes. It has a prevalence of 0.5 to one percen t. This translates to approximately two million persons in the United States. Furthermore, three to five percent of the population will have non-febrile seizures at some point in their life. Radio- telemetry of EEG has been recognized as a goal in the epil epsy monitoring community for many years. The application of UWB to EEG monitoring is new and innovative. It will offer a significant improvement to the field over the slower existing technology. No comparable device is currently available.

* information listed above is at the time of submission.

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