IMPROVED 3D MRI WITH CYLINDRICAL TRAJECTORIES
Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R44RR016397-01A1
Agency Tracking Number: RR016397
Amount:
$97,125.00
Phase:
Phase I
Program:
SBIR
Awards Year:
2002
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ADVANCED MRI TECHNOLOGY, LLC, 652 PETALUMA AVE, STE J, SEBASTOPOL, CA, 95472
DUNS:
N/A
HUBZone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Principal Investigator
Name: KAI RUPPERT
Phone: (707) 829-2933
Email: KAI.RUPPERT@ADVANCEDMRI.COM
Phone: (707) 829-2933
Email: KAI.RUPPERT@ADVANCEDMRI.COM
Business Contact
Name: DAVID FEINBERG
Phone: (707) 829-2340
Email: DAVID.FEINBERG@ADVANCEDMRI.COM
Phone: (707) 829-2340
Email: DAVID.FEINBERG@ADVANCEDMRI.COM
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): We are proposing the development of a
family of 3D single-slab MRI pulse sequences based on interleaved cylindrical
k-space trajectories. Spin-echo-train and gradient-echo versions will be
implemented on a state-of-the-art commercially available whole-body MR scanner
equipped with high-performance gradients. This trajectory type features a rare
combination of beneficial characteristics: high sampling efficiency, excellent
off-resonance behavior, low diffusion and flow sensitivity as well as
drastically reduced RF radiation exposure of the examined subject. Various
optimized sequence variants will be incorporated into 3D product sequences that
will benefit such diverse research areas as high-speed, high-resolution brain
MRJ, contrast-enhanced MRA, high-field MRI and hyperpolarized-gas MRI, The
success of each developmental step will be ensured by a stringent image quality
control that ensures that the signal-to-noise and the overall image artifact
load for a given set of sequence parameters is equal to or better than the
competing conventional MRI pulse sequences based on rectilinear or spiral
trajectories. During the commercialization phase the developed set of pulse
sequences will be ported for suitable hardware and software platforms of all
major MR hardware manufacturers. * Information listed above is at the time of submission. *