Noninvasive 3-D Assessment of Trabecular Microstructure

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 AR43536-01,
Agency Tracking Number: 29173
Amount: $99,958.00
Phase: Phase I
Program: SBIR
Awards Year: 1995
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
425 Lakeside Drive, Sunnyvale, CA, 94086
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Christopher Mitchell
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
The investigators will test the feasibility of developing a 3D X-ray microtomography scanner for trstudies in small animals, as further described by their abstract: A 3-D Computed Tomographic scannerobservation of trabecular bone microstructure and density of laboratory animals is proposed. This ReTomography (RAT) scanner will be capable of performing in vivo scans at 25- and 50-micrometer resolu6- and 12-mm fields of view. The novel introduction of a high- resolution high efficiency detector bscintillator/fiberoptics directly coupled to a thermoelectrically cooled 14-bit CCD camera allows imcompact geometry to achieve exceptionally high imaging throughput and image quality. The Phase I prodemonstrate the feasibility of 75-micrometer resolution and the ability to obtain images in under 20dose less than 1 rad. The RAT scanner will produce image data for 3-D matrix sizes of 256, 512 and 1

* Information listed above is at the time of submission. *

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