Noninvasive 3-D Assessment of Trabecular Microstructure

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,958.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 AR43536-01,
Award Id:
29173
Agency Tracking Number:
29173
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
425 Lakeside Drive, Sunnyvale, CA, 94086
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Christopher Mitchell
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
The investigators will test the feasibility of developing a 3D X-ray microtomography scanner for trstudies in small animals, as further described by their abstract: A 3-D Computed Tomographic scannerobservation of trabecular bone microstructure and density of laboratory animals is proposed. This ReTomography (RAT) scanner will be capable of performing in vivo scans at 25- and 50-micrometer resolu6- and 12-mm fields of view. The novel introduction of a high- resolution high efficiency detector bscintillator/fiberoptics directly coupled to a thermoelectrically cooled 14-bit CCD camera allows imcompact geometry to achieve exceptionally high imaging throughput and image quality. The Phase I prodemonstrate the feasibility of 75-micrometer resolution and the ability to obtain images in under 20dose less than 1 rad. The RAT scanner will produce image data for 3-D matrix sizes of 256, 512 and 1

* information listed above is at the time of submission.

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