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Non-Invasive, Continuous, Transdermal Glucose Monitor w/Actuator Control

Award Information
Agency: Department of Defense
Branch: Office of the Secretary of Defense
Contract: DAMD17-03-C-0048
Agency Tracking Number: O022-0461
Amount: $729,610.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
39255 Country Club Drive, Suite B-12
Farmington Hills, MI 48331
United States
DUNS: 014443423
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Hal Cantor, Ph.D.
 President and CTO
 (248) 553-9375
Business Contact
 Hal Cantor, Ph.D.
Title: President and CTO
Phone: (248) 553-9375
Research Institution

AST is developing a non-invasive methodology to continuously monitor blood glucose concentration. As opposed to employing near infrared spectroscopy, which suffers from limitations of sensitivity, stability, and repeatability, AST employs directmeasurement of glucose, via amperometric sensors, from minute amounts of interstitial fluid obtained transdermally. AST's miniature transdermal sampling system provides the capability to transduce the concentration of glucose and other biomoleculesincluding electrolytes, hormones, therapeutic drugs, etc., in real-time.Blood glucose concentrations can be used to determine metabolic status as well as to asses the degree of physiological and psychological stress experienced by the individual. Military troops can be instantly analyzed for their daily trend in bloodglucose, providing evidence for physiological and psychological stress. Utilizing this information, soldiers can be selected for an operation based upon their ability to handle the physiological and psychological stress associated with warfare. Further,AST's system can warn the soldier that they must ingest food or rest via internal alarms.Once outfitted with closed-loop control, automated infusion of insulin can be achieved to maintain euglycemia at all times. This process,

* Information listed above is at the time of submission. *

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