NOVEL BIOELECTRODE FOR NEUROSCIENCE APPLICATIONS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$499,994.00
Award Year:
1991
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
11361
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Advanced Surface Technology
12 Clematis Ave, Waltham, MA, 02154
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
A NOVEL BIOELECTRODE WILL BE FABRICATED FROM CONDUCTING POLYMERS. UNDER PROPER CONDITIONS, THIS BIOELECTRODE CAN BEELECTROCHEMICALLY REDUCED WITH RESULTING INCORPORATION OF NEUROTRANSMITTERS, SUCH AS ACETYLCHOLINE, -AMINOBUTYRATE, DOPAMINE, OR GLUTAMATE, INTO THE POLYMER MATRIX OF THE BIOELECTRODE. THE NEUROTRANSMITTER CAN REMAIN ENTRAPPED WITHIN THE CONDUCTING POLYMER MATRIX WHEN THE BIOELECTRODE IS KEPT AT A PROPER POTENTIAL. WHEN THE BIOELECTRODE IS KEPT AT A PROPER POTENTIAL. WHEN THE BIOELECTRODE IS STIMULATED BY AN ELECTRIC PULSE, THE ENTRAPPED NEUROTRANSMITTER CAN BE RELEASED FROM THE POLYMER MATRIX. THE NOVEL ELECTRODE DESCRIBED HERE IS THE PROTOTYPE FOR A DEVICE THAT COULD BE USED TO DELIVER SMALL AMOUNTS OF BIOMEDICALLY INTERESTING MATERIALS TO SPECIFIC LOCATIONS AT SPECIFIC TIMES.

* information listed above is at the time of submission.

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